Mathematical pressure volume models of the cerebrospinal fluid

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1 A pr 1 99 6 Mathematical Pressure Volume Models of the Cerebrospinal Fluid

Numerous mathematical models have emerged in the medical literature over the past two decades attempting to characterize the pressure and volume dynamics of the central nervous system compartment. These models have been used to study the behavior of this compartment under such pathological clinical conditions as hydrocephalus, head injury and brain edema. The number of different approaches has ...

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In six anaesthetised and ventilated dogs the CSF pulse pressure was compared with the volume-pressure response (VPR) during continuous inflation of an extradural balloon. Both pulse pressure and VPR increased linearly with the ventricular fluid pressure (VFP) up to a mean VFP of 60 mmHg. At this pressure a breakpoint occurred above which the CSF pulse pressure showed a steeper linear increase, ...

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Eyes with normal-pressure glaucoma and those with high-pressure glaucoma can show a similar optic nerve head appearance, while eyes with vascular optic neuropathies show a markedly different optic disc appearance. Factors in addition to intraocular pressure (IOP) may thus play a role in the pathogenesis of glaucomatous optic neuropathy. Clinical and experimental studies showed that (1) physiolo...

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Cerebrospinal fluid pressure (CSFP) interacts with intraocular pressure (IOP) and blood pressure to exert a major influence upon the eye, particularly the optic nerve head region. There is increased interest regarding the influence of CSFP upon disorders affecting this region, in particular glaucoma and idiopathic intracranial hypertension. Additionally, a high proportion of astronauts develop ...

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ژورنال

عنوان ژورنال: Applied Mathematics and Computation

سال: 1998

ISSN: 0096-3003

DOI: 10.1016/s0096-3003(97)10093-5